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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Products made in this industry2,035 PRODUCTS

ProductSourceFacilities
Test, Qualitative, Detection Of Dengue Igm And Igg AntibodiesFederal registry3
Test Reagents For Ethyl AlcoholFederal registry3
Test, Sickle CellFederal registry3
Test, Syphilis, TreponemalFederal registry3
Transducer, Ultrasonic, DiagnosticFederal registry3
Tray, Surgical, InstrumentFederal registry3
TrypsinFederal registry3
Tubing, Pressure And AccessoriesFederal registry3
Unit, Cryosurgical, AccessoriesFederal registry3
Vapocoolant DeviceFederal registry3
Whole Blood Plasma, Antigen, Antiserum, ControlFederal registry3
WineFederal registry3
Absorbable Collagen Hemostatic Agent With ThrombinFederal registry2
Accessories, Blood Circuit, HemodialysisFederal registry2
acidsCompany website2
Additively Manufactured, Preformed, Resin Denture ToothFederal registry2
Adhesives SealantsCompany website2
advanced materialsCompany website2
Agent, Absorbable Hemostatic, Non-Collagen BasedFederal registry2
AirbrushFederal registry2
Airway, NasopharyngealFederal registry2
Albumin, Fitc, Antigen, Antiserum, ControlFederal registry2
Allergen And Vaccine Delivery NeedlesFederal registry2
Alloy, Metal, BaseFederal registry2
all shoppable productsCompany website2
Alpha-1-Lipoprotein, Antigen, Antiserum, ControlFederal registry2
Alpha-2-Macroglobulin, Rhodamine, Antigen, Antiserum, ControlFederal registry2
Amalgamator, Dental, Ac-PoweredFederal registry2
Analyzer, Chemistry, Centrifugal, For Clinical UseFederal registry2
Analyzer, Chemistry, Micro, For Clinical UseFederal registry2
Antibodies, Saccharomyces Cerevisiae (S.Cerevisiae)Federal registry2
Antideoxyribonuclease, Streptococcus Spp.Federal registry2
Antigen, Antiserum, Control, Antithrombin IiiFederal registry2
Antigen, B. PertussisFederal registry2
Antigen, Cf, (Including Cf Control), Varicella-ZosterFederal registry2
Antigen, Cf, Psittacosis (Chlamydia Group)Federal registry2
Antigen(Complexed),Prostate Specific,(Cpsa)Federal registry2
Antigen, Fluorescent Antibody Test, Schistosoma MansoniFederal registry2
Antigens, All Groups, Salmonella Spp.Federal registry2
Antigens, Febrile, Slide And Tube, All Groups, Salmonella Spp.Federal registry2
Antigens, If, Toxoplasma GondiiFederal registry2
Antigens, Slide And Tube, Francisella TularensisFederal registry2
Anti-Human Globulin, Fta-Abs TestFederal registry2
Antisera, All Types, Escherichia ColiFederal registry2
Antisera, Cf, Adenovirus 1-33Federal registry2
Antisera, Cf, Equine Encephalitis Virus, Eee, WeeFederal registry2
Antisera, Control For Nontreponemal TestsFederal registry2
Antisera, Fluorescent, Brucella Spp.Federal registry2
Antisera, Hai, Influenza Virus A, B, CFederal registry2
Antisera, If, Toxoplasma GondiiFederal registry2

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.