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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Products made in this industry2,035 PRODUCTS

ProductSourceFacilities
Column Chromatography & Color Development, HydroxyprolineFederal registry2
Conductivity Rate, Urea NitrogenFederal registry2
Container, Liquid Medication, GraduatedFederal registry2
Continuous Glucose Monitor Informed Insulin Dose CalculatorFederal registry2
Control, HematocritFederal registry2
Cord, RetractionFederal registry2
Cotton, RollFederal registry2
Cresyl Violet AcetateFederal registry2
Cryptosporidium Spp.Federal registry2
Cuff, NerveFederal registry2
Curette, NasalFederal registry2
Curette, Suction, Endometrial (And Accessories)Federal registry2
custom formulationsCompany website2
Cystoscope And Accessories, Flexible/RigidFederal registry2
CytokeratinsFederal registry2
Cytomegalovirus (Cmv) Dna Quantitative AssayFederal registry2
Denture, Plastic, TeethFederal registry2
Device, Hematocrit MeasuringFederal registry2
Device, Microtiter Diluting/DispensingFederal registry2
Device, Percutaneous, BiopsyFederal registry2
DiastaseFederal registry2
Dilator, NasalFederal registry2
Dilator, Vessel, SurgicalFederal registry2
Dissector, Surgical, General & Plastic SurgeryFederal registry2
Dna-Probe, Human ChromosomeFederal registry2
Dna Probe, Nucleic Acid Amplification, ChlamydiaFederal registry2
Dna Specimen Collection, SalivaFederal registry2
Douche Apparatus, Vaginal, TherapeuticFederal registry2
Drape, Surgical, AntimicrobialFederal registry2
Drink, Glucose ToleranceFederal registry2
Drug-Eluting Peripheral Transluminal Angioplasty CatheterFederal registry2
Drug-Eluting Sinus StentFederal registry2
Ear Irrigation KitFederal registry2
Electrode, CutaneousFederal registry2
Electrode, Ion Selective (Non-Specified)Federal registry2
Electrophoretic Separation, LipoproteinsFederal registry2
Endoscopic Irrigation/Suction SystemFederal registry2
Enema KitFederal registry2
Enteral Syringes With Enteral Specific ConnectorsFederal registry2
Enzymatic Method, Alcohol Dehydrogenase, UltravioletFederal registry2
Enzymatic Method, BilirubinFederal registry2
Enzyme Immunoassay, Cortisol, SalivaryFederal registry2
Enzyme Immunoassay, MethotrexateFederal registry2
Enzyme Immunoassay, Valproic AcidFederal registry2
EpoxiesCompany website2
Eraser, Dental StainFederal registry2
Extended Depth Of Focus Intraocular LensFederal registry2
Face Mask Within The Scope Of The Face Mask And Barrier Face Covering Enforcement Policy Or Face Mask Umbrella EuaFederal registry2
Fastener, Fixation, Nondegradable, Soft TissueFederal registry2
Film, RadiographicFederal registry2

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.