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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Products made in this industry2,035 PRODUCTS

ProductSourceFacilities
films tapesCompany website2
Filter, Infusion LineFederal registry2
Finger CotFederal registry2
First Aid Kit Without DrugFederal registry2
Flow Cytometric Test System For Hematopoietic NeoplasmsFederal registry2
Flow Cytometry CalibratorFederal registry2
Flowmeter, Blood, CardiovascularFederal registry2
Fluorescent Immunoassay GentamicinFederal registry2
Fluorometer, For Clinical UseFederal registry2
Fluorometric, CalciumFederal registry2
Fluorometric, CortisolFederal registry2
Food ServiceCompany website2
Formulations, Mercuric Chloride For TissueFederal registry2
Gbs Culture Media, Selective And DifferentialFederal registry2
genesisCompany website2
GlutaraldehydeFederal registry2
Gram-Negative Bacteria And Associated Resistance MarkersFederal registry2
Gram Negative Identification PanelFederal registry2
Gram Positive Identification PanelFederal registry2
Group A Streptococcus Nucleic Acid Amplification Assay SystemFederal registry2
Guide, Needle, SurgicalFederal registry2
Guide, Surgical, InstrumentFederal registry2
Handle, ScalpelFederal registry2
Handpiece, Air-Powered, DentalFederal registry2
Hematoxylin, Iron, Weigert'SFederal registry2
Hematoxylin Weigert'SFederal registry2
Hemostatic Wound Dressing Without Thrombin Or Other BiologicsFederal registry2
herbicidesCompany website2
Hexane Extraction, Fluorescence, Vitamin EFederal registry2
High Pressure Liquid Chromatography, Tricyclic Antidepressant DrugsFederal registry2
High Throughput Dna Sequence AnalyzerFederal registry2
Hysteroscope (And Accessories)Federal registry2
Iga, Fitc, Antigen, Antiserum, ControlFederal registry2
Igd, Antigen, Antiserum, ControlFederal registry2
Immunoassay, Pregnanediol Glucuronide, Over The CounterFederal registry2
Implant, Eye ValveFederal registry2
Instrument, BiopsyFederal registry2
Instrument, CoagulationFederal registry2
Instrument, Coagulation, AutomatedFederal registry2
instrumentsCompany website2
Instruments, Dental HandFederal registry2
Instrument, Ultrasonic SurgicalFederal registry2
Insufflator, HysteroscopicFederal registry2
Insulin Pump Secondary DisplayFederal registry2
Integrated Continuous Glucose Monitor For Non-Intensive Glucose Management, Over-The-CounterFederal registry2
Interleukin 6Federal registry2
Internal Polymerase Chain Reaction Control, Not Assay SpecificFederal registry2
Intervertebral Fusion Device With Bone Graft, CervicalFederal registry2
Intervertebral Fusion Device With Integrated Fixation, LumbarFederal registry2
Intracardiac Patch Or Pledget, Biologically DerivedFederal registry2

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.