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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Products made in this industry2,035 PRODUCTS

ProductSourceFacilities
Intraocular LensFederal registry2
Iodine (Tincture)Federal registry2
Iron Chloride-WeigertFederal registry2
Irrigator, Powered NasalFederal registry2
Kit, Anaerobic IdentificationFederal registry2
Kit, Identification, EnterobacteriaceaeFederal registry2
Kit, Identification, Neisseria GonorrhoeaeFederal registry2
Kit, Screening, Staphylococcus AureusFederal registry2
Kit, Screening, TrichomonasFederal registry2
Kit, Surgical Instrument, DisposableFederal registry2
Kit, Test, Alpha-Fetoprotein For Neural Tube DefectsFederal registry2
Kit, Test,Alpha-Fetoprotein For Testicular CancerFederal registry2
Kit, Test (Donors), For Bloodborne PathogenFederal registry2
Lactoferrin, Antigen, Antiserum, ControlFederal registry2
Laparoscope, Gynecologic (And Accessories)Federal registry2
Lenses, Soft Contact, Daily WearFederal registry2
Lens, Guide, IntraocularFederal registry2
Lens, Intraocular, Toric OpticsFederal registry2
Lens, Multifocal IntraocularFederal registry2
Light, Operating, DentalFederal registry2
L-Leucine-4-Nitroanilide (Colorimetric), Leucine ArylamidaseFederal registry2
Lower Respiratory Microbial Nucleic Acid Detection SystemFederal registry2
Lubricant, Personal, Gamete, Fertilization, And Embryo CompatibleFederal registry2
Lymphocyte Separation MediumFederal registry2
Lynch Syndrome Test SystemFederal registry2
Marker, SkinFederal registry2
Media, Mounting, Oil SolubleFederal registry2
Meningitis/Encephalitis Pathogen Multiplex Nucleic Acid Detection SystemFederal registry2
Meprobamate Test SystemFederal registry2
Methenamine SilverFederal registry2
Method, Nephelometric, Immunoglobulins (G, A, M)Federal registry2
Methylene Blue ThiocyanateFederal registry2
Methyl GreenFederal registry2
Microbial Nucleic Acid Storage And Stabilization DeviceFederal registry2
Monitor, Microbial GrowthFederal registry2
Multiplex Immunoassay For T. Gondii, Rubella, Cytomegalovirus And Herpes Simplex Virus 1 And 2Federal registry2
Multiplex Nucleic Acid Detection System For Biothreat AgentsFederal registry2
Nasopharyngoscope (Flexible Or Rigid)Federal registry2
Nephelometric Inhibition Immunoassay, PhenobarbitalFederal registry2
Newborn Screening Specimen Collection PaperFederal registry2
Non-Medicated Topical Formulation For Treatment Of Erectile Dysfunction.Federal registry2
Nucleic Acid Amplification Test For The Quantitation Of Epstein-Barr Virus (Ebv) DnaFederal registry2
Ophthalmoscope, Battery-PoweredFederal registry2
Osmometer For Clinical UseFederal registry2
Other ProductsCompany website2
OtoscopeFederal registry2
Ovarian Adnexal Mass Assessment Score Test SystemFederal registry2
oxidesCompany website2
Oximeter To Measure HemoglobinFederal registry2
Pad, Menstrual, UnscentedFederal registry2

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.