Chemical Manufacturing

Name: Chemical Manufacturing facilities in the United States
Creator: FactoryRegistry
License: https://www.usa.gov/government-works

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Map of United States manufacturing facilities

Top cities

San Diego, CA Houston, TX Los Angeles, CA Pasadena, TX Chicago, IL South San Francisco, CA St. Louis, MO Irvine, CA Indianapolis, IN Phoenix, AZ Louisville, KY Denver, CO

Nearby industries

Nonmetallic Mineral Product Manufacturing (21,143)Plastics and Rubber Products Manufacturing (15,585)Wood Product Manufacturing (15,010)

Product lines reported here

Other chemical contract manufacturing services Manufacturing of cosmetics and other toilet preparations Manufacturing of all other inorganic chemicals Manufacturing of aromatics Manufacturing of commercial Manufacturing of miscellaneous end-use chemicals and chemical…

These are counts by industry: the Economic Census records what establishments in chemical manufacturing reported producing, and never names a plant.

Products made in this industry2,035 PRODUCTS

Product	Source	Facilities
Enzymatic Esterase--Oxidase, Cholesterol	Federal registry	12
Enzyme Immunoassay, Propoxyphene	Federal registry	12
Gas Chromatography, Methamphetamine	Federal registry	12
Instrumentation For Clinical Multiplex Test Systems	Federal registry	12
Radioimmunoassay, Testosterones And Dihydrotestosterone	Federal registry	12
Real Time Nucleic Acid Amplification System	Federal registry	12
Solvent, Adhesive Tape	Federal registry	12
Stain, Papanicolau	Federal registry	12
Stains, Hematology	Federal registry	12
Urinalysis Controls (Assayed And Unassayed)	Federal registry	12
Wright'S Stain	Federal registry	12
Antinuclear Antibody, Indirect Immunofluorescent, Antigen, Control	Federal registry	11
Assay, Glycosylated Hemoglobin	Federal registry	11
Calculator/Data Processing Module, For Clinical Use	Federal registry	11
Culture Media, Non-Selective And Non-Differential	Federal registry	11
Diazonium Colorimetry, Urobilinogen (Urinary, Non-Quant.)	Federal registry	11
Diluent, Blood Cell	Federal registry	11
Electrode, Ion Specific, Sodium	Federal registry	11
Fluid, Bouin'S	Federal registry	11
Hematoxylin Harris'S	Federal registry	11
Iodine, Grams	Federal registry	11
Methylene Blue, Tissue Stain	Federal registry	11
Radioimmunoassay, Tricyclic Antidepressant Drugs	Federal registry	11
Safranin	Federal registry	11
Set, Administration, Intravascular	Federal registry	11
Antinuclear Antibody (Enzyme-Labeled), Antigen, Controls	Federal registry	10
Applicator, Absorbent Tipped, Sterile	Federal registry	10
Automated Urinalysis System	Federal registry	10
Azo-Dyes, Colorimetric, Bilirubin & Its Conjugates (Urinary, Non-Quant.)	Federal registry	10
Clinical Sample Concentrator	Federal registry	10
Counter, Differential Cell	Federal registry	10
Diazo (Colorimetric), Nitrite (Urinary, Non-Quant)	Federal registry	10
Dressing, Wound, Hydrogel Without Drug And/Or Biologic	Federal registry	10
Dye-Indicator, Ph (Urinary, Non-Quantitative)	Federal registry	10
Electrode, Ion Specific, Potassium	Federal registry	10
Enzymatic Method, Creatinine	Federal registry	10
Enzyme Immunoassay, Non-Radiolabeled, Total Thyroxine	Federal registry	10
Formaldehyde (Formalin, Formol)	Federal registry	10
Gas, Calibration (Specified Concentration)	Federal registry	10
Immunoassay Method, Troponin Subunit	Federal registry	10
Immunohistochemistry Reagents And Kits	Federal registry	10
Indicator Method, Protein Or Albumin (Urinary, Non-Quant.)	Federal registry	10
Method, Enzymatic, Glucose (Urinary, Non-Quantitative)	Federal registry	10
Mixture, Hematology Quality Control	Federal registry	10
Multi-Analyte Respiratory Virus Antigen Detection Test	Federal registry	10
Respiratory Virus Panel Nucleic Acid Assay System	Federal registry	10
Slide Stainer, Automated	Federal registry	10
Solution, Decalcifier, Acid Containing	Federal registry	10
Stains, Dye Solution	Federal registry	10
Station, Pipetting And Diluting, For Clinical Use	Federal registry	10

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.