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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Products made in this industry2,035 PRODUCTS

ProductSourceFacilities
Splint, Hand, And ComponentsFederal registry2
Stainer, Tissue, AutomatedFederal registry2
Stapler, SkinFederal registry2
Strip, Polishing AgentFederal registry2
Strip, Temperature, Forehead, Liquid CrystalFederal registry2
Sudan IvFederal registry2
Sunglasses (Non-Prescription Including Photosensitive)Federal registry2
Susceptibility Test Cards, AntimicrobialFederal registry2
Susceptibility Test Plate, AntifungalFederal registry2
Susceptibility Test Powders, AntimycobacterialFederal registry2
Suture, Absorbable, Synthetic, Polyglycolic AcidFederal registry2
Suture, Nonabsorbable, Synthetic, PolypropyleneFederal registry2
Syringe, AntistickFederal registry2
Syringe, EntFederal registry2
Syringe, Restorative And Impression MaterialFederal registry2
System, Applicator, Radionuclide, ManualFederal registry2
System, Applicator, Radionuclide, Remote-ControlledFederal registry2
System, Detection, Bacterial, For Platelet Transfusion ProductsFederal registry2
System, Gastrointestinal Motility (Electrical)Federal registry2
System, Nucleic Acid Amplification, Mycobacterium Tuberculosis ComplexFederal registry2
System, Nucleic Acid Amplification Test, Dna, Carbapenem Non-Susceptible Gram Negative Organism, ColonyFederal registry2
System, Nucleic Acid Amplification Test, Dna, Methicillin Resistant Staphylococcus Aureus, Direct SpecimenFederal registry2
System, Skin ClosureFederal registry2
System, Test, Genotypic Detection, Resistant Markers, Staphylococcus ColoniesFederal registry2
System, Test, Her-2/Neu, IhcFederal registry2
System, Test, OsteocalcinFederal registry2
System, Test, Radioallergosorbent (Rast) ImmunologicalFederal registry2
System, Test, Radioallergosorbent (Rast) Immunological, Exempt AllergensFederal registry2
System, Test, Systemic Lupus ErythematosusFederal registry2
System, Test, Tumor Marker, For Detection Of Bladder CancerFederal registry2
System, Test, Tumor Marker, Monitoring, BladderFederal registry2
System, Transport, AerobicFederal registry2
System, X-Ray, Film Marking, RadiographicFederal registry2
TampFederal registry2
TapeCompany website2
TemplateFederal registry2
Test, Alpha Fetoprotein L3 Subfraction (Afp-L3%), For Hepatocellular Carcinoma Risk AssessmentFederal registry2
Test, Codeine, Employment And Insurance Testing, ExemptFederal registry2
Test, Cystatin CFederal registry2
Test, Donor, CmvFederal registry2
Test, Equipment, Automated Bloodborne PathogenFederal registry2
Test, Factor Ii G20210a Mutations, Genomic Dna PcrFederal registry2
Test, Factor V Leiden Mutations, Genomic Dna PcrFederal registry2
Test, Hepatitis B (B Antigen, B Surface Antigen, Be Antigen)Federal registry2
Test, Methaqualone, Employment And Insurance Testing, ExemptFederal registry2
Test, Morphine, Employment And Insurance Testing, ExemptFederal registry2
Test, Morphine, Over The CounterFederal registry2
Test, Nitrite, Urinary, Non-Quantitative, Over The CounterFederal registry2
Test, Propoxyphene, Employment And Insurance Testing, ExemptFederal registry2
Test, Qualitative And Quantitative Factor DeficiencyFederal registry2

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.