Chemical Manufacturing

Name: Chemical Manufacturing facilities in the United States
Creator: FactoryRegistry
License: https://www.usa.gov/government-works

28,137 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had 25801 establishments according to the Bureau of Labor Statistics in 2025. This register lists 28137 facilities. The West Point, PA Facility employs 8892 people as of 2025.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Map of United States manufacturing facilities

Top cities

San Diego, CA Houston, TX Los Angeles, CA Pasadena, TX Chicago, IL South San Francisco, CA St. Louis, MO Irvine, CA Indianapolis, IN Phoenix, AZ Louisville, KY Baltimore, MD

Nearby industries

Nonmetallic Mineral Product Manufacturing (21,235)Plastics and Rubber Products Manufacturing (15,887)Wood Product Manufacturing (15,247)

Product lines reported here

Other chemical contract manufacturing services Manufacturing of cosmetics and other toilet preparations Manufacturing of all other inorganic chemicals Manufacturing of aromatics Manufacturing of commercial Manufacturing of miscellaneous end-use chemicals and chemical…

These are counts by industry: the Economic Census records what establishments in chemical manufacturing reported producing, and never names a plant.

Products made in this industry2,065 PRODUCTS

Product	Source	Facilities
Enzyme Linked Immunoabsorbent Assay, Rubella	Federal registry	8
Enzyme Linked Immunoabsorbent Assay, Toxoplasma Gondii	Federal registry	8
Enzyme Linked Immunosorbent Assay, Herpes Simplex Virus, Hsv-1	Federal registry	8
Fibrinogen And Fibrin Split Products, Antigen, Antiserum, Control	Federal registry	8
Material, Impression Tray, Resin	Federal registry	8
Media And Components, Synthetic Cell And Tissue Culture	Federal registry	8
Multi-Target Respiratory Specimen Nucleic Acid Test Including Sars-Cov-2 And Other Microbial Agents	Federal registry	8
Nasal Spray, Ent Delivery	Federal registry	8
Over-The-Counter Covid-19 Antigen Test	Federal registry	8
Radioimmunoassay, Follicle-Stimulating Hormone	Federal registry	8
Radioimmunoassay, Prolactin (Lactogen)	Federal registry	8
Set, I.V. Fluid Transfer	Federal registry	8
Solution, Isotonic	Federal registry	8
Sterilant, Medical Devices	Federal registry	8
Test, Amphetamine, Over The Counter	Federal registry	8
Test, Barbiturate, Over The Counter	Federal registry	8
Test, Benzodiazepine, Over The Counter	Federal registry	8
Test, Cannabinoid, Over The Counter	Federal registry	8
Test, Cocaine And Cocaine Metabolites, Over The Counter	Federal registry	8
Test, Methadone, Over The Counter	Federal registry	8
Test, Methamphetamine, Over The Counter	Federal registry	8
Test, Tricyclic Antidepressants, Over The Counter	Federal registry	8
Toluidine Blue	Federal registry	8
Acid, Ascorbic, 2,4-Dinitrophenylhydrazine (Spectrophotometric)	Federal registry	7
Acid, Lactic, Enzymatic Method	Federal registry	7
Alcian Blue	Federal registry	7
Antimitochondrial Antibody, Indirect Immunofluorescent, Antigen, Control	Federal registry	7
Antinuclear Antibody, Antigen, Control	Federal registry	7
Bandage, Liquid	Federal registry	7
Bandage, Liquid, Skin Protectant	Federal registry	7
Bordetella Pertussis Dna Assay System	Federal registry	7
Container, Specimen, Sterile	Federal registry	7
Crown And Bridge, Temporary, Resin	Federal registry	7
Culture Media, Enriched	Federal registry	7
Culture Media, General Nutrient Broth	Federal registry	7
Culture Media, Selective And Differential	Federal registry	7
Electrode, Ion Specific, Calcium	Federal registry	7
Electrode Measurement, Blood-Gases (Pco2, Po2) And Blood Ph	Federal registry	7
Enzyme Controls (Assayed And Unassayed)	Federal registry	7
Ferritin, Antigen, Antiserum, Control	Federal registry	7
Filler, Bone Void, Calcium Compound	Federal registry	7
Fixative, Formalin-Containing	Federal registry	7
Gold Chloride	Federal registry	7
Hexokinase, Glucose	Federal registry	7
Ige, Antigen, Antiserum, Control	Federal registry	7
Kit, Quality Control For Blood Banking Reagents	Federal registry	7
Legionella, Spp., Elisa	Federal registry	7
Lipoprotein, Low-Density, Antigen, Antiserum, Control	Federal registry	7
Material, Tooth Shade, Resin	Federal registry	7
Mesh, Surgical	Federal registry	7

Search all 28,137 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of NOV 2026, FactoryRegistry lists 28,137 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,143 facilities listed.

How many chemical manufacturing facilities are still operating?

15,240 of the 28,137 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.