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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Plants in this industry27,897 FACILITIES

FacilityCityStateEmployeesStatus
Dental Technologies INCLincolnwoodIL20–99 ACTIVE
Dexcom, INC.San DiegoCA— ACTIVE
Diamond Chemical CO INCEast RutherfordNJ— ACTIVE
Diasorin INCStillwaterMN500+ ACTIVE
Dinsmore & Associates, LLCIrvineCA20–99 ACTIVE
Dipsol of America INCLivoniaMI20–99 ACTIVE
Diversey INC. - FlorenceFlorenceKY— ACTIVE
Dixie Chemical Company, INC.PasadenaTX100–499 ACTIVE
Dlc Laboratories, INC.ParamountCA20–99 ACTIVE
Dover Chemical CorporationDoverOH100–499 ACTIVE
Dow Silicones CorporationCarrolltonKY100–499 ACTIVE
Drytech INCCookstownNJ20–99 ACTIVE
Dsm Nutritional ProductsKingstreeSC100–499 ACTIVE
Dte Calvert City LLCCalvert CityKY100–499 ACTIVE
Dupont Electronic Materials International, LLCMarlboroughMA100–499 ACTIVE
Dupont Pontchartrain SiteLa PlaceLA100–499 ACTIVE
Durez CORPNiagara FallsNY20–99 ACTIVE
Dynalene INCWhitehallPA20–99 ACTIVE
Dyno Nobel INCGrahamKY20–99 ACTIVE
Dyno Nobel INC. - St. Helens PlantDeer IslandOR20–99 ACTIVE
Eaglepicher Technologies LLCJoplinMO— ACTIVE
Easiway Systems, INC.DelanoMN20–99 ACTIVE
East Kansas Agri Energy LLCGarnettKS20–99 ACTIVE
Eastman Chemical CompanyKingsportTN— ACTIVE
Eastman Chemical Company, Texas OperationsLongviewTX500+ ACTIVE
Eastman Specialties CORPChestertownMD20–99 ACTIVE
Ecc Corrosion INCWisconsin RapidsWI20–99 ACTIVE
Eckart America CORPPainesvilleOH20–99 ACTIVE
Eckert & Ziegler Isotope Products, INC.ValenciaCA20–99 ACTIVE
Eddyville Chlor-alkali LLCEddyvilleIA20–99 ACTIVE
Eichrom Technologies LLCLisleIL20–99 ACTIVE
Elanco Clinton LaboratoriesClintonIN500+ ACTIVE
Electric Cable CompoundsNaugatuckCT20–99 ACTIVE
Electric Hydrogen CODevensMA100–499 ACTIVE
Electronics for Imaging INCYpsilantiMI20–99 ACTIVE
Elementis Specialties INCSt. LouisMO20–99 ACTIVE
Elite OctaneAtlanticIA20–99 ACTIVE
Elutia INC.GaithersburgMD— ACTIVE
Embalmers' Supply Company, theEast LymeCT— ACTIVE
Emd Acquisition LLCHendersonNV— ACTIVE
Enchem America, INCCommerceGA20–99 ACTIVE
Enerco CORPPottervilleMI20–99 ACTIVE
Energizer Battery Manufacturing INCMariettaOH20–99 ACTIVE
Enviro Tech International INCMelrose ParkIL— ACTIVE
Epmar CorporationWhittierCA20–99 ACTIVE
Epsilyte LLCPeruIL20–99 ACTIVE
Equinox Chemicals, LLCAlbanyGA— ACTIVE
Equistar Chemicals, LP (0243020004)Fairport HarborOH20–99 ACTIVE
Espin Technologies, INC.ChattanoogaTN— ACTIVE
Estron Chemical INCCalvert CityKY20–99 ACTIVE

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.