Chemical Manufacturing

Name: Chemical Manufacturing facilities in the United States
Creator: FactoryRegistry
License: https://www.usa.gov/government-works

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Map of United States manufacturing facilities

Top cities

San Diego, CA Houston, TX Los Angeles, CA Pasadena, TX Chicago, IL South San Francisco, CA St. Louis, MO Irvine, CA Indianapolis, IN Phoenix, AZ Louisville, KY Denver, CO

Nearby industries

Nonmetallic Mineral Product Manufacturing (21,143)Plastics and Rubber Products Manufacturing (15,585)Wood Product Manufacturing (15,010)

Product lines reported here

Other chemical contract manufacturing services Manufacturing of cosmetics and other toilet preparations Manufacturing of all other inorganic chemicals Manufacturing of aromatics Manufacturing of commercial Manufacturing of miscellaneous end-use chemicals and chemical…

These are counts by industry: the Economic Census records what establishments in chemical manufacturing reported producing, and never names a plant.

Products made in this industry2,035 PRODUCTS

Product	Source	Facilities
System, Hemoglobin, Automated	Federal registry	7
System, Test, Anticardiolipin Immunological	Federal registry	7
Test, Amphetamine, Over The Counter	Federal registry	7
Test, Barbiturate, Over The Counter	Federal registry	7
Test, Benzodiazepine, Over The Counter	Federal registry	7
Test, Cannabinoid, Over The Counter	Federal registry	7
Test, Cocaine And Cocaine Metabolites, Over The Counter	Federal registry	7
Test, Methadone, Over The Counter	Federal registry	7
Test, Methamphetamine, Over The Counter	Federal registry	7
Test, Opiates, Employment And Insurance Testing, Exempt	Federal registry	7
Test, Propoxyphene, Over The Counter	Federal registry	7
Test, Tricyclic Antidepressants, Over The Counter	Federal registry	7
Accessories, Soft Lens Products	Federal registry	6
Acid, Folic, Radioimmunoassay	Federal registry	6
Acid, Uric, Uricase (Colorimetric)	Federal registry	6
Agent, Tooth Bonding, Resin	Federal registry	6
Albumin, Antigen, Antiserum, Control	Federal registry	6
Alkaline Picrate, Colorimetry, Creatinine	Federal registry	6
Antibodies, Anti-Cyclic Citrullinated Peptide (Ccp)	Federal registry	6
Antistreptolysin - Titer/Streptolysin O Reagent	Federal registry	6
Apolipoproteins	Federal registry	6
Assayed External Control Material For Microbiology Nucleic Acid Amplification (Nat) Assays	Federal registry	6
Autoantibodies, Endomysial(Tissue Transglutaminase)	Federal registry	6
Calibrator For Hemoglobin And Hematocrit Measurement	Federal registry	6
Cement, Dental	Federal registry	6
Cleanser, Denture, Over The Counter	Federal registry	6
Container, Specimen, Non-Sterile	Federal registry	6
Coverslips, Microscope Slide	Federal registry	6
Culture Media, Non-Selective And Differential	Federal registry	6
Culture Media, Selective Broth	Federal registry	6
Electrosurgical, Cutting & Coagulation & Accessories	Federal registry	6
Enzyme Immunoassay, Digoxin	Federal registry	6
Enzyme Linked Immunoabsorbent Assay, Mumps Virus	Federal registry	6
Enzyme Linked Immunoabsorbent Assay, Rubeola Igg	Federal registry	6
Enzyme Linked Immunosorbent Assay, Herpes Simplex Virus, Hsv-2	Federal registry	6
Epstein-Barr Virus, Other	Federal registry	6
Fixative, Acid Containing	Federal registry	6
Formulations, Paraffin, All	Federal registry	6
Haptoglobin, Antigen, Antiserum, Control	Federal registry	6
Igg, Antigen, Antiserum, Control	Federal registry	6
Immunochemical, Thyroglobulin Autoantibody	Federal registry	6
Influenza A And Influenza B Multiplex Nucleic Acid Assay	Federal registry	6
Kappa, Antigen, Antiserum, Control	Federal registry	6
Lambda, Antigen, Antiserum, Control	Federal registry	6
Ldl & Vldl Precipitation, Cholesterol Via Esterase-Oxidase, Hdl	Federal registry	6
Ldl & Vldl Precipitation, Hdl	Federal registry	6
Lipase Hydrolysis/Glycerol Kinase Enzyme, Triglycerides	Federal registry	6
Mesh, Surgical	Federal registry	6
Mucicarmine	Federal registry	6
Nadh Oxidation/Nad Reduction, Alt/Sgpt	Federal registry	6

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.