 Aerospace Engineering LLC | Santa Ana | 20–99 | ● ACTIVE |
 Cognita Labs, LLC | Santa Ana | — | ● ACTIVE |
 Gs Solutions, INC. | Santa Ana | — | ● ACTIVE |
 Heart Rate, INC. | Santa Ana | — | ● ACTIVE |
| SSSign Specialists CORP | Santa Ana | — | ● ACTIVE |
 Ace Link Industrial INC | Santa Ana | — | ● ACTIVE |
 Bio Orthopedic Lab LLC | Santa Ana | — | ● ACTIVE |
 Xs Scuba, INC | Santa Ana | — | ● ACTIVE |
| MPMicro Precision Swiss LLC Dba | Santa Ana | — | ◐ LIKELY ACTIVE |
 Image O and P, LLC | Santa Ana | — | ◐ LIKELY ACTIVE |
 Pinsco, INC. | Santa Ana | — | ◐ LIKELY ACTIVE |
| TSTotl Seal INC | Santa Ana | — | ◐ LIKELY ACTIVE |
| SSStanco Signage Systems, INC | Santa Ana | — | ▲ REPORTED CLOSED |
| AMAckley Metal Products | Santa Ana | — | ◇ UNVERIFIED |
| AMAdvanced Medical Optics | Santa Ana | — | ◇ UNVERIFIED |
| WTWaterline Technologies, Inc., Psoc | Santa Ana | — | ◇ UNVERIFIED |
| AMAftco Mfg Co, INC | Santa Ana | 20–99 | ◐ LIKELY ACTIVE |
| CGComeco Group, INC | Santa Ana | — | ◐ LIKELY ACTIVE |
 Medtronic USA | Santa Ana | 500+ | ◐ LIKELY ACTIVE |
| MPMicro Precision Swiss, LLC (dba Orchid MPS, Orchid Santa Ana, Orchid Keller, Orchid Torrance) | Santa Ana | 100–499 | ◐ LIKELY ACTIVE |
| SCSouthern California Prosthetics INC. | Santa Ana | — | ◐ LIKELY ACTIVE |
| UCUS269 CA Santa Ana | Santa Ana | 1–19 | ◐ LIKELY ACTIVE |
| ACAardvark Clay & Supplies | Santa Ana | — | ◇ UNVERIFIED |
| ACAdvanced Composite Products & Technology INC | Santa Ana | — | ◇ UNVERIFIED |
| AIAmusement Industry C-vii, LLC | Santa Ana | — | ◇ UNVERIFIED |
| BFBaxter Fenwal | Santa Ana | — | ◇ UNVERIFIED |
| BSBob Siemon Designs | Santa Ana | — | ◇ UNVERIFIED |
| BOBrasstech Old Main Site | Santa Ana | — | ◇ UNVERIFIED |
| BCBurtin Corporation | Santa Ana | — | ◇ UNVERIFIED |
| CWCalifornia Wire Edm | Santa Ana | — | ◇ UNVERIFIED |
| CDChromium Dental II LLC | Santa Ana | — | ◇ UNVERIFIED |
| CDChromium Dental Ii LLC Dba Spectrum Dental Lab | Santa Ana | — | ◇ UNVERIFIED |
| DLDiamond Laboratory | Santa Ana | — | ◇ UNVERIFIED |
| DBDyer Business Park | Santa Ana | — | ◇ UNVERIFIED |
 Edwards Lifesciences - Daimler 3009 | Santa Ana | — | ◇ UNVERIFIED |
| FSFreudenberg-nok Sealing Technologies | Santa Ana | — | ◇ UNVERIFIED |
| GDGarcia Dental Office | Santa Ana | — | ◇ UNVERIFIED |
| GDGildred Development | Santa Ana | — | ◇ UNVERIFIED |
| HCHigh-tech Coatings | Santa Ana | — | ◇ UNVERIFIED |
| HTHome Team Yards, INC. | Santa Ana | — | ◇ UNVERIFIED |
| IGIron Grip Barbell CO INC | Santa Ana | — | ◇ UNVERIFIED |
| JVJns Vision INC | Santa Ana | — | ◇ UNVERIFIED |
| KCKerr Corporation | Santa Ana | — | ◇ UNVERIFIED |
| MMMallinckrodt Medical INC | Santa Ana | — | ◇ UNVERIFIED |
| MSManeri Sign Company Dba Statewide Safety Systems | Santa Ana | — | ◇ UNVERIFIED |
| MIMedtronic Inc., Heart Valves Div. | Santa Ana | — | ◇ UNVERIFIED |
| MLMerchfarm LLC | Santa Ana | — | ◇ UNVERIFIED |
| MMicrotech | Santa Ana | — | ◇ UNVERIFIED |
| MRMontgomery Radiographic Services | Santa Ana | — | ◇ UNVERIFIED |
| MEMrw Extrusion INC. | Santa Ana | — | ◇ UNVERIFIED |
