| RRReynolds & Reynolds Electronics, Inc. | Bethlehem | PA | Electrical Equipment, Appliance & Component Manufacturing335999 | 20-99 | ◐ LIKELY ACTIVE |
| RHR H Sheppard CO INC | Hanover | PA | Primary Metal Manufacturing331511 | — | ◐ LIKELY ACTIVE |
| RIRichardsApex, Inc | Philadelphia | PA | Petroleum and Coal Products Manufacturing324191 | 20-99 | ◐ LIKELY ACTIVE |
| RMRichlyn Mfg Inc | Erie | PA | Fabricated Metal Product Manufacturing332721 | 20-99 | ◐ LIKELY ACTIVE |
Riehl Quality Storage Barns LLC | Kinzers | PA | Wood Product Manufacturing321992 | 1-19 | ◐ LIKELY ACTIVE |
| RMR&N Manufacturing, LLC | Pittsburgh | PA | Fabricated Metal Product Manufacturing332311 | 20-99 | ◐ LIKELY ACTIVE |
| RFRobinson Fans PA Plant 1 | Zelienople | PA | Machinery Manufacturing333413 | 100-499 | ◐ LIKELY ACTIVE |
Rocal Corporation | Warrington | PA | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| RCRock-tenn CO Stroudsburg Mill | Delaware Water Gap | PA | Paper Manufacturing322130 | — | ◐ LIKELY ACTIVE |
| RFRogers Foam Corp/morrisville | Morrisville | PA | Textile Mills313320 | — | ◐ LIKELY ACTIVE |
| RSRussell Std Mfg Mercer | Mercer | PA | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| SASa Alloys | Columbia | PA | Primary Metal Manufacturing331314 | — | ◐ LIKELY ACTIVE |
Sandmeyer Steel CO | Philadelphia | PA | Fabricated Metal Product Manufacturing332313 | — | ◐ LIKELY ACTIVE |
| SPSanofi Pasteur/swiftwater Fac | Swiftwater | PA | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| SRSchuylkill River Tank Farm | Philadelphia | PA | Petroleum and Coal Products Manufacturing324110 | — | ◐ LIKELY ACTIVE |
| SPSeward Power Plant | New Florence | PA | Chemical Manufacturing325610 | — | ◐ LIKELY ACTIVE |
| SSSfi - Shippensburg Plant | Shippensburg | PA | Food Manufacturing311511 | — | ◐ LIKELY ACTIVE |
| STSignal Technologies, Inc. | Erie | PA | Electrical Equipment, Appliance & Component Manufacturing335122 | 20-99 | ◐ LIKELY ACTIVE |
| SASignature Alum INC - Greenville Facility | Greenville | PA | Primary Metal Manufacturing331314 | — | ◐ LIKELY ACTIVE |
| SDSignature Door Inc. | Altoona | PA | Wood Product Manufacturing321911 | 20-99 | ◐ LIKELY ACTIVE |
| SCSika Corporation | Fairless Hills | PA | Nonmetallic Mineral Product Manufacturing327390 | 20-99 | ◐ LIKELY ACTIVE |
| SMSilberline Mfg CO - Lincoln Dr Plant | Tamaqua | PA | Chemical Manufacturing325130 | — | ◐ LIKELY ACTIVE |
| SCSilvi Concrete Morrisville Plt | Fairless Hills | PA | Nonmetallic Mineral Product Manufacturing327320 | 500+ | ◐ LIKELY ACTIVE |
| SRSimpson Reinforcing Inc | Arnold | PA | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| SCSippel CO INC Dba Sippel Steel Fab | Ambridge | PA | Fabricated Metal Product Manufacturing332312 | 100-499 | ◐ LIKELY ACTIVE |
| SPSmc Powder Metallurgy | Galeton | PA | Fabricated Metal Product Manufacturing332117 | — | ◐ LIKELY ACTIVE |
| STSnap Tite INC Union City Site | Union City | PA | Fabricated Metal Product Manufacturing332721 | — | ◐ LIKELY ACTIVE |
| SISouthco Inc/concordville | Concordville | PA | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| SVSpecialized Vehicles Corp/montgomery Plt | Montgomery | PA | Transportation Equipment Manufacturing336211 | — | ◐ LIKELY ACTIVE |
| SBSpecialty Bakers LLC | Marysville | PA | Food Manufacturing311812 | 100-499 | ◐ LIKELY ACTIVE |
| SWSpectra Wood | State College | PA | Furniture and Related Product Manufacturing337211 | 20-99 | ◐ LIKELY ACTIVE |
| SMSperanza Machining, INC. | Export | PA | Fabricated Metal Product Manufacturing332710 | 1-19 | ◐ LIKELY ACTIVE |
| SPSpray Products | Plymouth Meeting | PA | Chemical Manufacturing325510 | 100-499 | ◐ LIKELY ACTIVE |
| STSps Technologies - Aerospace Products Division | Jenkintown | PA | Fabricated Metal Product Manufacturing332722 | — | ◐ LIKELY ACTIVE |
| SFStandard Forged Products | Mc Kees Rocks | PA | Fabricated Metal Product Manufacturing332111 | 20-99 | ◐ LIKELY ACTIVE |
| SBStanley Black and Decker Inc/allentown | Allentown | PA | Fabricated Metal Product Manufacturing332999 | — | ◐ LIKELY ACTIVE |
| SCStella-jones CORP | Du Bois | PA | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| SJStella Jones Corp/mcalisterville | Mc Alisterville | PA | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
Stewart-amos Equipment CO | Harrisburg | PA | Transportation Equipment Manufacturing336211 | 20-99 | ◐ LIKELY ACTIVE |
| SMSt Marys Box Company Inc | St Marys | PA | Paper Manufacturing322211 | 20-99 | ◐ LIKELY ACTIVE |
| SBStraub Brewery, Inc. | St. Marys | PA | Beverage and Tobacco Product Manufacturing312120 | 20-99 | ◐ LIKELY ACTIVE |
| SCSun Chem Corp/hunting Park Plt | Philadelphia | PA | Chemical Manufacturing325910 | — | ◐ LIKELY ACTIVE |
| SDSunny Dell Specialty LLC | Oxford | PA | Food Manufacturing311615 | 20-99 | ◐ LIKELY ACTIVE |
| SSupelco | Bellefonte | PA | Chemical Manufacturing325199 | — | ◐ LIKELY ACTIVE |
| SOSuperior Outdoor Products | New Holland | PA | Plastics and Rubber Products Manufacturing326121 | 100-499 | ◐ LIKELY ACTIVE |
| SESutphen East Corporation | Lake Ariel | PA | Transportation Equipment Manufacturing336120 | 20-99 | ◐ LIKELY ACTIVE |
| SWSwab Wagon Company | Elizabethville | PA | Transportation Equipment Manufacturing336111 | 20-99 | ◐ LIKELY ACTIVE |
| SISwf Industrial | Wrightsville | PA | Fabricated Metal Product Manufacturing332312 | 100-499 | ◐ LIKELY ACTIVE |
| STSylvin Technologies INC | Denver | PA | Chemical Manufacturing325991 | — | ◐ LIKELY ACTIVE |
| SASyst a Matic Tool & Design | Meadville | PA | Machinery Manufacturing333319 | 1-19 | ◐ LIKELY ACTIVE |