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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Plants in this industry27,897 FACILITIES

FacilityCityStateEmployeesStatus
Acrotech Biopharma INC.East WindsorNJ20–99 ACTIVE
Adhesive Compounders, INC.Des MoinesIA— ACTIVE
Advanced Composites, INC.NashvilleTN100–499 ACTIVE
Advanced Ionics, INCNew BerlinWI20–99 ACTIVE
Advanced Prototyping INCRochester HillsMI— ACTIVE
Advanced Refrigerant Technologies LLCLeague CityTX— ACTIVE
Advanced Technical Finishing, LLCHuntsvilleAL— ACTIVE
Advance Products & Systems LLCScottLA— ACTIVE
Aero Clean Technologies LLCLynchburgVA— ACTIVE
Aerogreen Solutions, LLCClear BrookVA— ACTIVE
Aerojet Rocketdyne of De, INCCanoga ParkCA— ACTIVE
Affimedix, INC.HaywardCA— ACTIVE
Agas US INCBowling GreenOH— ACTIVE
Agc Electronics AmericaHillsboroOR100–499 ACTIVE
Aiping Pharmaceutical, INCHauppaugeNY— ACTIVE
Airgas Usa, LLCSalemNH— ACTIVE
Airgas Usa, LLCSacramentoCA— ACTIVE
Airgas Usa, LLCIndependenceOH— ACTIVE
Ajay North America LLCPowder SpringsGA20–99 ACTIVE
Alchem Laboratories CorporationAlachuaFL— ACTIVE
Alder Energy, LLCLouisvilleCO— ACTIVE
Aldevron Madison LLCMadisonWI— ACTIVE
Alere San Diego, INC.PomonaCA— ACTIVE
Alexandria Professional, LLCClarenceNY— ACTIVE
Allens Nutech INCTylerTX20–99 ACTIVE
Alliance Medical Products INCIrvineCA— ACTIVE
Alphapet, INC.DecaturAL100–499 ACTIVE
Alpha Teknova, INC.HollisterCA— ACTIVE
Altathera Pharmaceuticals LLCChicagoIL20–99 ACTIVE
Altrazeal Life Sciences INCAddisonTX— ACTIVE
Amaya Solutions INCPlant CityFL— ACTIVE
American Laboratory Products Company, LTDSalemNH— ACTIVE
American Regent INCShirleyNY— ACTIVE
American Screening L.l.c.ShreveportLA— ACTIVE
Amerstem, INC.CamarilloCA— ACTIVE
Ames Research Laboratories, INC.SalemOR— ACTIVE
Amneal Pharmaceuticals of New York, LLCBrookhavenNY500+ ACTIVE
Amphastar Pharmaceuticals, INC.Rancho CucamongaCA— ACTIVE
Ams Coatings, INC.Santa AnaCA— ACTIVE
Amtec CORPClear LakeSD— ACTIVE
Andelyn Biosciences INCColumbusOH100–499 ACTIVE
Andy-oxy CO INCAshevilleNC20–99 ACTIVE
Anthro Energy INCAlamedaCA— ACTIVE
Anver CORPHudsonMA— ACTIVE
Apex Engineering Products CORPAuroraIL— ACTIVE
Apex Water and Process INCSaint MichaelMN— ACTIVE
Aphena Pharma SolutionsEastonMD— ACTIVE
Applied Biocode INCSanta Fe SpringsCA— ACTIVE
Applied Plastics Technology, INC.BristolRI20–99 ACTIVE
Appli-tec INCSalemNH20–99 ACTIVE

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.