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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Plants in this industry27,897 FACILITIES

FacilityCityStateEmployeesStatus
Aqua Laboratories, INCAmesburyMA20–99 ACTIVE
Aquaphoenix Scientific, LLCMidlandVA20–99 ACTIVE
Aqua Science, INCColumbusOH— ACTIVE
Arbor Halides INCAnn ArborMI— ACTIVE
Arcutis Biotherapeutics, INC.Westlake VillageCA— ACTIVE
Argonaut Manufacturing Services, INC.CarlsbadCA— ACTIVE
Argonics, INC.GwinnMI— ACTIVE
Arlington Scientific, INCSpringvilleUT— ACTIVE
Armstrong PharmaceuticalsCantonMA100–499 ACTIVE
Arris Composites, INC.BerkeleyCA— ACTIVE
Ascendia Pharmaceuticals, INC.North BrunswickNJ— ACTIVE
Ascent Chemicals Danville, INC.DanvilleVA20–99 ACTIVE
Ascent Pharmaceuticals INCCentral IslipNY100–499 ACTIVE
A-s Medication Solutions LLCLibertyvilleIL— ACTIVE
Associates of Cape Cod, INC.East FalmouthMA— ACTIVE
Astellas Pharma Us, INC.NorthbrookIL500+ ACTIVE
Atlas Carbon, LLCGilletteWY— ACTIVE
Atlas Minerals & Chemicals INCMertztownPA20–99 ACTIVE
Austin Powder CompanyClevelandOH100–499 ACTIVE
Automat Solutions INCSan LeandroCA— ACTIVE
Avid Bioservices INCTustinCA— ACTIVE
Axiom Diagnostics, INC.TampaFL— ACTIVE
Azurity Pharmaceuticals INCWilmingtonMA— ACTIVE
Baebies, INC.DurhamNC— ACTIVE
Bandit Industries, INC.RemusMI— ACTIVE
Basf CorporationFlorham ParkNJ— ACTIVE
Baxter Healthcare INCHaywardCA100–499 ACTIVE
Bayer CORP Consumer Care DivMorristownNJ— ACTIVE
B Braun US Pharmaceutical Mfg LLCIrvineCA500+ ACTIVE
Beckman Coulter, INCBreaCA— ACTIVE
Becton, Dickinson and CompanyMilpitasCA— ACTIVE
Bedoukian Research, INC.DanburyCT100–499 ACTIVE
Belzona, INC.MiamiFL— ACTIVE
Berry Film Products Company INC.AugustaKY100–499 ACTIVE
Beta BionicsIrvineCA100–499 ACTIVE
Beutlich Pharmaceuticals, LLCBunnellFL— ACTIVE
Binding Site, Inc., theSan DiegoCA— ACTIVE
Biofire Defense LLCSalt Lake CityUT— ACTIVE
Biogen U.s. CorporationCambridgeMA100–499 ACTIVE
Biogx, INCHooverAL— ACTIVE
Bioivt, LLCWoodburyNY— ACTIVE
Biolegend, INC.San DiegoCA— ACTIVE
Biologics, INC.CaryNC— ACTIVE
Biomune COLenexaKS— ACTIVE
Bionutrients Ag LLCWabashIN20–99 ACTIVE
Bio Rad Laboratories INCHerculesCA— ACTIVE
Bio-rad Laboratories, INC.HerculesCA— ACTIVE
Bio Rad Laboratories WoodinvilleWoodinvilleWA100–499 ACTIVE
Biosafe Systems, LLCEast HartfordCT— ACTIVE
Biotechnique LLCYorkPA— ACTIVE

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.