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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Plants in this industry27,897 FACILITIES

FacilityCityStateEmployeesStatus
Birchwood Laboratories LLCEden PrairieMN20–99 ACTIVE
Blaine Laboratories, INC.Santa Fe SpringsCA— ACTIVE
Bowlus Road Chief LLCOxnardCA— ACTIVE
Bpi Labs, LLCLargoFL— ACTIVE
Brammer Bio Ma, LLCCambridgeMA— ACTIVE
Brewer International, IncorporatedVero BeachFL— ACTIVE
Bristol-myers Squibb CompanyLawrencevilleNJ— ACTIVE
Britt Industries, INCArlington HeightsIL— ACTIVE
Brp Manufacturing COLimaOH20–99 ACTIVE
Bruckman Rubber COHastingsNE— ACTIVE
Butler Acquisitions, LTDSouth Saint PaulMN— ACTIVE
Byk USA INCLouisvilleKY20–99 ACTIVE
Calibrescientific Us, INC.VancouverWA— ACTIVE
Cambridge Isotope Laboratories, INCAndoverMA— ACTIVE
Campbell TransportationNewellWV20–99 ACTIVE
Canary Renewables CORP.StocktonCA— ACTIVE
Cancer Diagnostics, INC.DurhamNC— ACTIVE
CarefusionEl PasoTX— ACTIVE
Carroll Coatings CO INCProvidenceRI— ACTIVE
Cartridge Actuated Devices, INCAndoverNJ— ACTIVE
Catalent Pharma SolutionsSt PetersburgFL— ACTIVE
Cdg Environmental, LLCAllentownPA— ACTIVE
C. E. Frey Engineering LLCDuarteCA— ACTIVE
Cell Marque CORP.RocklinCA100–499 ACTIVE
Cemcoat INCLos AngelesCA— ACTIVE
Century Pharmaceuticals, INC.IndianapolisIN20–99 ACTIVE
Cerus CorporationConcordCA— ACTIVE
Chardon Laboratories, INCReynoldsburgOH— ACTIVE
Charm Industrial INCSan FranciscoCA— ACTIVE
Charm Sciences INCLawrenceMA— ACTIVE
Chembio Diagnostic Systems INC.MedfordNY— ACTIVE
Chemisphere CorporationSaint LouisMO— ACTIVE
Chempacific CORPBaltimoreMD— ACTIVE
Chemtreat, INC.Glen AllenVA500+ ACTIVE
Christeyns North America, LLCGreenvilleNC— ACTIVE
Cie Norfolk Gns, LLCNorfolkNE20–99 ACTIVE
Clariant CORPBelenNM— ACTIVE
Cliawaived, INC.CarlsbadCA— ACTIVE
Clorox COOaklandCA— ACTIVE
Colonial Research Chemical CORPNorfolkNE— ACTIVE
Colorado Serum CompanyDenverCO20–99 ACTIVE
Columbia Chemical CORPBrunswickOH— ACTIVE
Combined Systems INCJamestownPA— ACTIVE
Commonwealth Agri-energy, LLCHopkinsvilleKY— ACTIVE
Complete Welders SupplyNapaCA— ACTIVE
Concorde Specialty Gases, INC.EatontownNJ— ACTIVE
Contec, INCSpartanburgSC— ACTIVE
Continental Refining Company LLCSomersetKY1–19 ACTIVE
Contract Pharmacal CORP.HauppaugeNY20–99 ACTIVE
Coopersurgical INCTrumbullCT— ACTIVE

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.